Xiaoyu Xing and Yan Zhao
Org. Biomol. Chem., 2018,16, 1627-1631
DOI:
10.1039/C8OB00100F,
Communication
Conformational flexibility in the host's structure is often considered detrimental to its binding. Flexible pseudo-crown ethers with aromatic donor/acceptor groups at the chain ends, however, displayed enhanced binding affinity and selectivity, particularly when the direct binding interactions were compromised by unfavorable solvents.