Issue 6, 2015

Nickel-catalyzed decarboxylative arylation of azoles with perfluoro- and nitrobenzoates

Abstract

This manuscript describes a Ni-catalyzed method for the direct arylation of azoles using benzoates. Perfluorophenyl and 2-nitrobenzoates participate in these reactions to afford the corresponding products in modest to good yields. The efficiency of the arylations with perfluorobenzoates is highly dependent on both the degree and position of fluorine atoms in the benzoates.

Graphical abstract: Nickel-catalyzed decarboxylative arylation of azoles with perfluoro- and nitrobenzoates

Supplementary files

Article information

Article type
Research Article
Submitted
31 Qun 2015
Accepted
15 Agd 2015
First published
12 Cax 2015

Org. Chem. Front., 2015,2, 726-729

Nickel-catalyzed decarboxylative arylation of azoles with perfluoro- and nitrobenzoates

J. M. Crawford, K. E. Shelton, E. K. Reeves, B. K. Sadarananda and D. Kalyani, Org. Chem. Front., 2015, 2, 726 DOI: 10.1039/C5QO00040H

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