Amin GhavamiNejad, Brian Lu, Adria Giacca and Xiao Yu Wu
Nanoscale, 2019,11, 10167-10171
DOI:
10.1039/C9NR01687B,
Communication
We have introduced a non-hormonal hyperglycemia treatment strategy by using an injectable glucose-responsive boronic acid- zwitterionic nanogel. The synthesized system, similar to an artificial liver, is capable of storing/releasing glucose at high/low blood glucose concentrations. In vivo performance revealed that the injection of the nanogels can effectively regulate blood glucose in type 1 diabetic rats for at least 6 hours.