Perspective
The importance of indirect hotspots when prioritizing research in green chemical synthesis
An indirect hotspot is a process step that may cause little harm on its own but has a strong influence on a very harmful tstep (the direct hotspot) and thereby the total harm of the process.
Machine learning-driven design of single-atom catalysts for carbon dioxide valorization to high-value chemicals: a review of photocatalysis, electrocatalysis, and thermocatalysis
The research about photocatalytic, electrocatalytic, and thermocatalytic CO2 reduction, with single-atom catalysts (SACs).
Highly efficient synthesis of tert-butyl esters using (Boc)2O under solvent/base-free electromagnetic milling conditions: a new reaction model
A novel and efficient method has been developed for the synthesis of tert-butyl esters using (Boc)2O as the tert-butyl source, facilitated by electromagnetic milling.
Recycling of polystyrene waste to mono-aromatic hydrocarbons via intermittent thermal scission
Tunable depolymerization–repolymerization during polystyrene pyrolysis enables selective production of mono-aromatic hydrocarbons (MAHs), achieving >90% liquid yield with ~95% MAHs. The strategy applies to various polystyrene feedstocks.
High ionic conductivity conjugated artificial solid electrolyte interphase enabling stable lithium metal batteries
The functional artificial SEI layer (CPAN@ZnO), featuring high ionic conductivity, effectively enhances interface stability of Li metal and improves cycling performance of Li-limited cells.
Microgel-engineered temperature-responsive microcapsules at liquid interfaces for sequential biocatalytic reactions
Microgels, with their adjustable deformability and responsiveness, offer a promising alternative to prepare microcompartments via template-directed assembly onto emulsion droplets.
Feasibility study of an electrochemical hydrogen looping system for indirect ocean capture
Electrochemical hydrogen looping is a recently developed, sustainable technology to address decentralized anthropogenic carbon dioxide emissions by indirectly retrieving CO2 from oceans.
Asymmetric defective site-triggered triple synergistic modulation in nanoconfined aerogel for superior electrochemical conversion of low-concentration nitrate into ammonia
A synergistic strategy combining nanoconfinement with defect engineering is proposed to boost nitrate electroreduction via concentrating nitrate, enhancing nitrate adsorption, accelerating water dissociation, and suppressing hydrogen evolution.
Paper
Two-step continuous flow aerobic oxidation of cannabidiol to cannabinoquinone derivatives
A two-step continuous flow synthesis using molecular oxygen to prepare cannabidiol quinone derivative, Etrinabdione, under sustainable conditions is reported.
Paper
A microbial factory for bio-indigo synthesis: demonstration of sustainable denim dying
A engineered microbial factory that converts renewable carbon into indigo, eliminating hazardous synthesis, lowering energy use, and avoiding toxic byproducts.
Tandem electrocatalytic benzylic alcohol oxidation and aldol condensation for efficient valuable α,β-unsaturated ketone production
This study presents a one-step electrosynthesis method for α,β-unsaturated ketones using an Au/CuO cooperative catalyst for selective oxidation of aromatic alcohols followed by aldol condensation, achieving green and efficient production.
Paper
Integrated technoeconomic and environmental assessment of biogenic polyurethane production
An integrated technoeconomic and life-cycle assessment revealed that maximising the biogenic carbon content in polyurethane synthesis based on the isocyanate intermediate route enhances economic performance without reducing the global warming impact.
Paper
Efficient continuous flow oxidation of furfural to maleic anhydride using O2 as a green oxidant
Continuous flow operation greatly improved the oxidation of biorenewable furfural to maleic anhydride, achieving improved productivity while adhering to green chemistry principles.
Tuning the electronic structure of phosphonic acid-based deep eutectic solvents for synergistic catalytic oxidative desulfurization
The bifunctional phosphonic acid-based (PDES) ZnCl2/2PIA, synthesized via coordination and hydrogen bonding, exhibited efficient oxidative desulfurization of diesel fuel and high cycle-regeneration stability.
Paper
Bio-oil derived polyesteramides as water-degradable replacements for polyethylene
Polyesteramides derived from Ethiopian mustard seed bio-oil possess commercially relevant thermomechanical properties and are chemically recyclable and water-degradable.
Paper
Recovery and reuse of homogeneous palladium catalysts via organic solvent nanofiltration: application in the synthesis of AZD4625
Using OSN, a homogeneous Pd catalyst in AZD4625 synthesis is separated and reused for five cycles, maintaining over 90% conversion.
Paper
Toward industrial C8 production: oxygen intrusion drives renewable n-caprylate production from ethanol and acetate via intermediate metabolite production
A simplified open culture chain elongation process with ethanol and acetate to produce renewable n-caprylate without adding yeast extract showed a trophic hierarchy between aerobic, facultative anaerobic, and fully anaerobic microbial species.
Tensile-strain-driven interstitial Ru doping structure on an FeCoP/FF electrode accelerates the reaction kinetics of water electrolysis
This work creatively developed a strain-driven interstitial Ru doping strategy to synthesize an interstitially Ru doped-FeCoP/FF electrode with 2.32% tensile strain.
Paper
Thermodynamically leveraged solventless aerobic deconstruction of polyethylene-terephthalate plastics over a single-site molybdenum-dioxo catalyst
This study reports the ambient catalytic depolymerization of PET under solvent-free conditions, using a carbon-supported single-site molybdenum-dioxo catalyst.
Paper
Carbon dioxide-negative composite materials: an economically viable solution for CO2 sequestration
Carboxylating lignin and lignite fillers to sequester CO2 in composite materials.
Anion doping promotes electrocatalyst reconfiguration for efficient C–C bond cleavage of 4-methylcyclohexanol
P doping promotes structural reconfiguration in nickel-based catalysts, forming an NiOOH/Ni2P interface that facilitates electrooxidation of 4-methylcyclohexanol.
Natural wood as a lithium metal host
Natural wood with an exquisite 3D interconnected hierarchical porous structure is employed as a Li host. The wood host is conducive to regulating Li plating/stripping behavior, leading to reduced polarization and prolonged lifespan.
The sustainable and catalytic synthesis of N,N-alkylated fatty amines from fatty acids and esters
The reductive amination of fatty acids (FAs) and fatty acid methyl esters (FAMEs) has been identified as a green and effective method to produce N,N-dimethylalkylamines (ADMAs).
Paper
A waste-minimized protocol for electrochemical reductive amination and its environmental assessment
We report an efficient protocol for electrochemical reductive amination. A careful combination of reaction medium and electrolyte has allowed waste minimization and improved sustainability, as detailed by the environmental assessment of the process.
“One-for-all” on-demand multifunctional fluorescent amphoteric polymers achieving breakthrough leather eco-manufacturing evolution
The proposed “all-in-one” strategy enables the creation of multifunctional materials for tanning, retanning, fatliquoring, and dyeing, simplifying leather manufacturing to meet market demands while delivering significant environmental benefits.
About this collection
Welcome to our online rolling collection of the hottest work published in Green Chemistry. Here we feature all of the 2025 articles highlighted as HOT by our Editors and Referees. Congratulations to all those featured!