Issue 61, 2020

Biomedical applications of dendritic fibrous nanosilica (DFNS): recent progress and challenges

Abstract

Dendritic fibrous nanosilica (DFNS), with multi-component and hierarchically complex structures, has recently been receiving significant attention in various fields of nano-biomedicine. DFNS is an emerging class of mesoporous nanoparticles that has attracted great interest due to unique structures such as open three-dimensional dendritic superstructures with large pore channels and highly accessible internal surface areas. This overview aims to study the application of DFNS towards biomedical investigations. This review is divided into four main sections. Sections 1–3 are related to the synthesis and characterization of DFNS. The biomedical potential of DFNS, such as cell therapy, gene therapy, immune therapy, drug delivery, imaging, photothermal therapy, bioanalysis, biocatalysis, and tissue engineering, is discussed based on advantages and limitations. Finally, the perspectives and challenges in terms of controlled synthesis and potential nano-biomedical applications towards future studies are discussed.

Graphical abstract: Biomedical applications of dendritic fibrous nanosilica (DFNS): recent progress and challenges

Article information

Article type
Review Article
Submitted
16 may 2020
Accepted
18 sen 2020
First published
08 okt 2020
This article is Open Access
Creative Commons BY license

RSC Adv., 2020,10, 37116-37133

Biomedical applications of dendritic fibrous nanosilica (DFNS): recent progress and challenges

M. Shaban and M. Hasanzadeh, RSC Adv., 2020, 10, 37116 DOI: 10.1039/D0RA04388E

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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