Issue 22, 2020

Advances and challenges in metallic nanomaterial synthesis and antibacterial applications

Abstract

Multi-drug resistant bacterial infection has become one of the most serious threats to global public health. The preparation and application of new antibacterial materials are of great significance for solving the infection problem of bacteria, especially multi-drug resistant bacteria. The exceptional antibacterial effects of metal nanoparticles based on their unique physical and chemical properties make such systems ideal for application as antibacterial drug carriers or self-modified therapeutic agents both in vitro and in vivo. Metal nanoparticles also have admirable clinical application prospects due to their broad antibacterial spectrum, various antibacterial mechanisms and excellent biocompatibility. Nevertheless, the in vivo structural stability, long-term safety and cytotoxicity of the surface modification of metal nanoparticles have yet to be further explored and improved in subsequent studies. Herein, we summarized the research progress concerning the mechanism of metal nanomaterials in terms of antibacterial activity together with the preparation of metal nanostructures. Based on these observations, we also give a brief discussion on the current problems and future developments of metal nanoparticles for antibacterial applications.

Graphical abstract: Advances and challenges in metallic nanomaterial synthesis and antibacterial applications

Article information

Article type
Review Article
Submitted
12 yan 2020
Accepted
25 fev 2020
First published
26 fev 2020

J. Mater. Chem. B, 2020,8, 4764-4777

Advances and challenges in metallic nanomaterial synthesis and antibacterial applications

Z. Guo, Y. Chen, Y. Wang, H. Jiang and X. Wang, J. Mater. Chem. B, 2020, 8, 4764 DOI: 10.1039/D0TB00099J

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