Issue 33, 2024

Mechanochemical generation of aryne

Abstract

Mechanical force is unique in promoting unusual reaction pathways and especially for the generation of reactive intermediates sometimes inaccessible to other forms of activation. The mechanochemical generation of reactive species could find application in synthetic and materials chemistry alike. However, the nature of these reactive intermediates has been mostly limited to radicals or carbenes. Here, we present a new mechanophore that generates a reactive aryne intermediate upon dissociation of a benzocyclobutene (BCB) core via a force-promoted retro [2 + 2] cycloaddition.

Graphical abstract: Mechanochemical generation of aryne

Supplementary files

Article information

Article type
Edge Article
Submitted
17 iyn 2024
Accepted
24 iyl 2024
First published
08 avq 2024
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2024,15, 13181-13184

Mechanochemical generation of aryne

Q. Cheng and G. De Bo, Chem. Sci., 2024, 15, 13181 DOI: 10.1039/D4SC03968H

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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