Recent advances in the functionalization of saturated cyclic amines

Abstract

In recent decades, increasing efforts have been made for the development of more efficient and sustainable methods for the functionalization of saturated cyclic amines. This is mainly due to the following two facts: (1) simple cyclic amines are readily available with low cost; and (2) functionalized cyclic amines are synthetically and biologically highly valuable in that they are found in numerous natural products, pharmaceuticals and fine chemicals. In this review, the most recent advances in the C–H, C–N and C–C bond functionalization of saturated cyclic amines are summarized.