Hongmei Zhang, Chenglong Xu, Jie Liu, Xiaohong Li, Lin Guo and Xinming Li
Chem. Commun., 2015,51, 7031-7034
DOI:
10.1039/C5CC01005E,
Communication
We report the design and synthesis of a novel probe (1) for ALP assay by incorporating a self-immolative linker between a phosphate moiety and resorufin. Because of its good biocompatibility and rapid cell internalization, this probe also exhibited great potential for real-time monitoring of endogenous phosphatase activity in living cells.
