Upconversion nanohybrids for NIR-induced photorepair of DNA etheno adducts†
Laura
Francés-Soriano, 
ab
Gemma M.
Rodríguez-Muñiz,
c
Paloma
Lizondo-Aranda,
c
María
González-Béjar
*a
and
Virginie
Lhiaubet-Vallet
*c
ab
Gemma M.
Rodríguez-Muñiz,
c
Paloma
Lizondo-Aranda,
c
María
González-Béjar
*a
and
Virginie
Lhiaubet-Vallet
*c
Abstract
Here, we report NIR-triggered photorepair of DNA damages via photosensitization by using well-known upconversion nanohybrids consisting of ytterbium and erbium co-doped core–shell upconversion nanoparticles (UCs) and Rose Bengal (UC@RB). Specifically, two purine-derived etheno adducts (1,N6-etheno-2′-deoxyadenosine (εdA) and 1,N2-etheno-2′-deoxyguanosine (εdG)) have been used as proof of concept.
- This article is part of the themed collection: UPCON24 – Upconversion Nanomaterials
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