* Corresponding authors

^a Graduate Institute of Clinical Medicine, School of Medicine, College of Medicine, Taipei Medical University, No. 250, Wuxing St., Taipei 11031, Taiwan

^b Division of Rheumatology, Immunology and Allergy, Taipei Medical University Hospital, No. 252, Wuxing St., Taipei 11031, Taiwan

^c Department of Chemical Engineering, National Taiwan University of Science and Technology, No. 43, Sec. 4, Keelung Rd., Taipei 10607, Taiwan

^d Department of Materials Science and Engineering, Vanung University, No. 1, Van Nung Rd, Chung-Li City, Taiwan

^e School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, No. 250, Wuxing St., Taipei 11031, Taiwan

^f Graduate Institute of Clinical Medicine, Department of General Medicine, School of Medicine, College of Medicine, Taipei Medical University, No. 250, Wuxing St., Taipei 11031, Taiwan
E-mail: sylin@tmu.edu.tw
Fax: +886-2-27390214
Tel: +886-2-27361661 ext. 3903

^g Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, No. 250, Wuxing St., Taipei 11031, Taiwan
E-mail: liuyc@tmu.edu.tw
Fax: +886-2-27356689
Tel: +886-2-27361661 ext. 3155

^h Biomedical Mass Imaging Research Center, Taipei Medical University, No. 250, Wuxing St., Taipei 11031, Taiwan