Issue 64, 2017

A highly selective ratiometric fluorescent probe for the cascade detection of Zn2+ and H2PO4 and its application in living cell imaging

Abstract

A simple ratiometric sensor (L1) for the cascade detection of Zn2+ and H2PO4 with high selectivity was reported based on the intermolecular charge transfer (ICT) mechanism. This new sensor could distinguish Zn2+ from Cd2+, and features high fluorescence quantum yield with L1 (0.45) and L1–Zn2+ (0.27). There is a good linear relationship between the fluorescence ratio I525 nm/I430 nm upon addition of Zn2+ and the limit of detection (LOD) was evaluated to be 41.0 nM. Furthermore, the in situ prepared L1–Zn2+ complex also displayed good selectivity and ratiometric response for H2PO4 and the detection limit of L1–Zn2+ was found to be 49.0 nM. L1 exhibits permeability and can been applied to the detection of intracellular Zn2+ and H2PO4 in HepG-2 cells.

Graphical abstract: A highly selective ratiometric fluorescent probe for the cascade detection of Zn2+ and H2PO4− and its application in living cell imaging

Associated articles

Supplementary files

Article information

Article type
Paper
Submitted
20 Jul 2017
Accepted
12 Aug 2017
First published
21 Aug 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 40615-40620

A highly selective ratiometric fluorescent probe for the cascade detection of Zn2+ and H2PO4 and its application in living cell imaging

K. Du, S. Niu, L. Qiao, Y. Dou, Q. Zhu, X. Chen and P. Zhang, RSC Adv., 2017, 7, 40615 DOI: 10.1039/C7RA08020D

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements