Copper-catalyzed direct C–H phosphorylation of N-imino isoquinolinium ylides with H-phosphonates†
Xing-Guo
Zhang 
*a
and
Chen-Liang
Deng
*a
*a
and
Chen-Liang
Deng
*a
Abstract
A new and efficient protocol for the synthesis of phosphorus-containing isoquinoline skeletons via copper-catalyzed direct C–H phosphorylation of N-iminoisoquinolinium ylides with H-phosphonates has been described. A variety of N-iminoisoquinolinium ylides reacted under the ligand and oxidant free conditions smoothly to afford phosphorylated isoquinolines in moderate to excellent yields.
Please wait while we load your content...
