Issue 4, 2021

A mitochondria-targeted dual-functional aggregation-induced emission luminogen for intracellular mitochondrial imaging and photodynamic therapy

Abstract

A mitochondria-targeted dual-functional aggregation-induced emission luminogen, TPP-TPEDCH, was rationally designed and developed for intracellular mitochondrial imaging and photodynamic therapy. TPP-TPEDCH clearly showed the movements of mitochondria at various time points. Moreover, both in vitro and in vivo results demonstrated its excellent ROS generation ability and strong antitumor activity.

Graphical abstract: A mitochondria-targeted dual-functional aggregation-induced emission luminogen for intracellular mitochondrial imaging and photodynamic therapy

Associated articles

Supplementary files

Article information

Article type
Communication
Submitted
12 Dec 2020
Accepted
14 Jan 2021
First published
19 Jan 2021

Biomater. Sci., 2021,9, 1232-1236

A mitochondria-targeted dual-functional aggregation-induced emission luminogen for intracellular mitochondrial imaging and photodynamic therapy

Y. Zhang, W. Huang, X. Tan, J. Wang, Y. Zhao, J. Hu and S. Wang, Biomater. Sci., 2021, 9, 1232 DOI: 10.1039/D0BM02099K

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