* Corresponding authors

^a Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, China
E-mail: lyxu@stu.edu.cn
Fax: +86-754-88900847
Tel: +86-754-88900460

^b Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, China
E-mail: nmli@stu.edu.cn
Fax: +86-754-88900847
Tel: +86-754-88900413

^c Institute of Oncologic Pathology, Shantou University Medical College, Shantou 515041, China

^d Department of Experimental Animal Center, Shantou University Medical College, Shantou 515041, China

^e Bioanalytical Laboratory, Shantou University Medical College, Shantou 515041, China