* Corresponding authors

^a Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan
E-mail: tlcheng@kmu.edu.tw

^b Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan

^c Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan

^d Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

^e School of Medicine for International Students, I-Shou University, Kaohsiung, Taiwan

^f Department of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan

^g Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan

^h Department of Biochemistry, Kaohsiung Medical University, Kaohsiung, Taiwan
E-mail: c00jsw00@kmu.edu.tw