* Corresponding authors

^a University of Groningen, Department of Drug Design, A. Deusinglaan 1, Groningen, The Netherlands

^b Alzheimer's Research UK Oxford Drug Discovery Institute, University of Oxford, Oxford OX3 7FZ, UK

^c Jagiellonian University, Faculty of Chemistry, Department of Crystal Chemistry and Crystal, Physics, Biocrystallography Group, Gronostajowa 2, 30-387 Krakow, Poland

^d Palackȳ University, CATRIN, Department of Innovative Chemistry, Šlechtitelů 241/27, 779 00, Olomouc – Holice, Czech Republic
E-mail: alexander.domling@upol.cz