* Corresponding authors

^a Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
E-mail: wangyan_sg@126.com, yanwang@shutcm.edu.cn

^b Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
E-mail: qili@shutcm.edu.cn

^c Department of Chemistry, University of South Florida, 4202 E. Fowler Avenue, Tampa, FL 33620, USA
E-mail: jianfengcai@usf.edu