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Abstract | Cited by

Electrostatic interaction-mediated enzymatic-hydrolysis of poly(lactide)-containing nanoscale assemblies is described. At physiological pH, degradable core–shell morphologies with charged shells can readily attract or repel enzymes carrying opposite or similar charges, respectively.

Graphical abstract: Programmed hydrolysis of nanoassemblies by electrostatic interaction-mediated enzymatic-degradation

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