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2-(2-Propylsulfinyl)benzyl glycoside was designed as a new type of glycosyl donor which could be activated via remote mode. This glycosyl donor and its reduced form could act as active and latent donors respectively in a latent-active glycosylation strategy. Details of the discovery of this novel glycosyl donor are reported in this article.

Graphical abstract: Glycosylation via remote activation of anomeric leaving groups: development of 2-(2-propylsulfinyl)benzyl glycosides as novel glycosyl donors

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