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Flexible electronic devices that are lightweight and wearable are critical for personal healthcare systems, which are not restricted by time and space. To monitor human bio-signals in a non-invasive manner, skin-conforming, highly sensitive, reliable, and sustainable healthcare monitoring devices are required. In this review, we introduce flexible and wearable sensors based on engineered functional nano/micro-materials with unique sensing capabilities for detection of physical and electrophysiological vital signs of humans. In addition, we investigate key factors for the development of user-interactive healthcare devices that are customizable, wearable, skin-conforming, and monolithic (design), and have long-term monitoring capability with sustainable power sources. Finally, we describe potential challenges of developing current wearable healthcare devices for applications in fitness, medical diagnosis, prosthetics, and robotics.

Graphical abstract: Wearable and flexible sensors for user-interactive health-monitoring devices

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