Polar effects in Grignard attack at the oxygen atoms of carbonyl groups
Abstract
The yields of benzyl ethers relative to those of 4-benzylphenols from reaction of substituted benzylmagnesium chlorides with 6-acetoxy-2,6-dimethylcyclo-hexa-2,4-dienone are unaflected by the nature of the substituents, but the yields of both products increase, relative to those of 3-benzylphenols, with increasing electron-donating powers of the substituents.