New synthesis of purines by the reaction of diethyl azodicarboxylate with 6-alkylaminouracils
Abstract
Treatment of 6-alkylamino-uracils with excess of diethyl azodicarboxylate gave the respective xanthine derivatives; reaction of 6-amino-5-(1,2-diethoxycarbonyl-hydrazino)-1,3-dimethyluracil with aryl aldehydes also gave the corresponding xanthine derivatives.