Interconversion of 8,2′-O-cycloadenosine and 2′,3′-anhydro-8-oxyadenosine
Abstract
Treatment of 8,2′-O-cycloadenosine (1a) and its benzoylation product with alkali gives 2′,3′-anhydro-8-oxyadenosine (2a) and its 6-N-benzoyl derivative (2b), respectively; under mildly alkaline conditions (2a) is converted back into (1a).