Preparation of 4-aryl- and 4-heteroaryl-pyridines: regiospecific nucleophilic attack γ to a quaternary nitrogen atom
Abstract
1-(2,6-Dimethyl-4-oxopyridin-1-yl)pyridinium cation reacts with aryl and heteroaryl Grignard reagents to give regiospecifically the corresponding 4-arylpyridines.