Chemoenzymatic routes to chiral (non-racemic) cyclopropanes. Preparation of a key intermediate for the synthesis of (1R)-cis-pyrethroids
Abstract
The microbial oxidation product 2 (X = Br) has been converted into the chiral (non-racemic) cyclopropane 11, a synthon for the commercially significant (1R)-cis-pyrethroid class of insecticides.