Issue 1, 1997

Nanogram-scale derivatization of hydroxy groups for highly sensitive HPLC/MS/CD detection

Abstract

A strategy for performing submicrogram-scale structural studies of saponins and related compounds is worked out by: (i) naphthoylation to sensitize HPLC detection by fluorescence as well as configurational studies by exciton coupled CD; and (ii) ω-cyanoundecanoylation to increase LC/MS sensitivity (ca. 100-fold).

Article information

Article type
Paper

Chem. Commun., 1997, 43-44

Nanogram-scale derivatization of hydroxy groups for highly sensitive HPLC/MS/CD detection

N. Zhao, J. Guo, L. Lo, N. Berova, K. Nakanishi, G. T. Haupert, M. Warrack and A. A. Tymiak, Chem. Commun., 1997, 43 DOI: 10.1039/A605800K

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