Issue 3, 1998

Stereoselective intramolecular aldol reactions of (4R)-3-(3-oxobutanoyl)-1,3-thiazolidine-4-carboxylates believed to be directed by ‘self-induced’ axial chirality

Abstract

Essentially complete retention of configuration accompanies the base-induced aldol reaction of the thiazolidinecarboxylate 6c to give the fused heterocycles 7c and 8c and their retroaldol–acylation reactions to give the bicycle 9c.

Article information

Article type
Paper

Chem. Commun., 1998, 299-300

Stereoselective intramolecular aldol reactions of (4R)-3-(3-oxobutanoyl)-1,3-thiazolidine-4-carboxylates believed to be directed by ‘self-induced’ axial chirality

A. G. Brewster, C. S. Frampton, M. B. Mitchell, J. Jayatissa, R. J. Stoodley and S. Vohra, Chem. Commun., 1998, 299 DOI: 10.1039/A707388G

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