Control of the iodination reaction on activated aromatic residues in peptidesElectronic supplementary information (ESI) available: experimental and characterization data for compounds 4, 6, 7–13. See http://www.rsc.org/suppdata/cc/b0/b003064n/

Abstract

By using a slight molar excess of the IPy₂BF₄ reagent in an acid containing medium, activated aromatic residues on Tyr derivatives and peptides selectively react yielding, as major products, the monoiododerivatives; this level of reaction control cannot be achieved by other iodinating methods.