Issue 18, 2000

Short cuts toward forskolin synthesis: a pentacyclic approachCCDC 182/1719. See http://www.rsc.org/suppdata/cc/b0/b004515m/ for crystallographic files in .cif format.

Abstract

A practical synthetic route for the preparation of forskolin intermediate 20 is described. Previously reported lactone 3 was converted to 20 through intermediate 16. The main feature of this work lies in the formation and the cleavage of a tetracyclic intermediate for the stereochemical control in the formation of the tricyclic core of forskolin.

Supplementary files

Article information

Article type
Communication
Submitted
06 Jun 2000
Accepted
11 Jul 2000
First published
25 Aug 2000

Chem. Commun., 2000, 1737-1738

Short cuts toward forskolin synthesis: a pentacyclic approach

M. Leclaire, R. Levet, F. Ferreira, P. Ducrot and J. Lallemand Louis Ricard, Chem. Commun., 2000, 1737 DOI: 10.1039/B004515M

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