A unique example of a core-modified bis-proline peptide self-assembling into an infinite hydrogen-bonded β-sheet ribbon: crystal structure of Z-ProNH(CH2)2NHPro-Z
Abstract
The crystal structure of Z-ProNH(CH2)2NHPro-Z exhibits an extended backbone, with occurrence of both a cis and a trans conformation preceding the two prolyl residues, that self-assembles into an infinite hydrogen-bonded β-sheet ribbon.