Issue 10, 2002
From the journal:

Chemical Communications

The regioselective preparation of 1,3-diketones within a micro reactor

Charlotte Wiles,a   Paul Watts,a   Stephen J. Haswell*a  and  Esteban Pombo-Villarb  

* Corresponding authors

a Department of Chemistry, Faculty of Science and the Environment, University of Hull, Cottingham Road, Hull, UK
E-mail: s.j.haswell@hull.ac.uk
Fax: 01482 466416
Tel: 01482 465475

b Nervous Systems Research, WSJ-386.07.15, Novartis Pharma Ltd, Basel, Switzerland

Abstract

We demonstrate a simple method for the regioselective preparation of 1,3-diketones within a micro reactor from silyl enol ethers where the products are free from both competing O-acylation and diacylation products.

Graphical abstract: The regioselective preparation of 1,3-diketones within a micro reactor

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Article information

DOI
https://doi.org/10.1039/B201220K
Article type
Communication
Submitted
06 Feb 2002
Accepted
02 Apr 2002
First published
11 Apr 2002

Chem. Commun., 2002, 1034-1035

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The regioselective preparation of 1,3-diketones within a micro reactor

C. Wiles, P. Watts, S. J. Haswell and E. Pombo-Villar, Chem. Commun., 2002, 1034 DOI: 10.1039/B201220K

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