Issue 17, 2002

3′,4′-trans-Linked bicyclic nucleosides locked in S-type conformations

Abstract

A novel class of 3′,4′-trans-linked bicyclic nucleosides with locked S-type furanose conformations is introduced by synthesis of two model derivatives; one was obtained by cyclic ether formation and the other by ring-closing metathesis methodology.

Graphical abstract: 3′,4′-trans-Linked bicyclic nucleosides locked in S-type conformations

Article information

Article type
Communication
Submitted
24 May 2002
Accepted
04 Jul 2002
First published
12 Aug 2002

Chem. Commun., 2002, 1888-1889

3′,4′-trans-Linked bicyclic nucleosides locked in S-type conformations

H. Thomasen, M. Meldgaard, M. Freitag, M. Petersen, J. Wengel and P. Nielsen, Chem. Commun., 2002, 1888 DOI: 10.1039/B205031E

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