Issue 18, 2002
From the journal:

Chemical Communications

An efficient synthesis of endo,exo-furofuranone derivatives

Nigel A. Swain,a   Richard C. D. Brown*a  and  Gordon Brutonb  

* Corresponding authors

a Department of Chemistry, University of Southampton, Southampton, UK
E-mail: rcb1@soton.ac.uk
Fax: +44 (0) 2380 596805
Tel: +44 (0) 2380 594108

b GlaxoSmithKline Pharmaceuticals, New Frontiers Science Park, Harlow, Essex, UK

Abstract

The ring openings of 1-acetyl-4-phenyl-3-oxabicyclo[3.1.0]hexane afforded α-acetyl-γ-butyrolactones that underwent a novel diazo-transfer reaction, followed by C–H insertion, to provide a series of endo,exo-furofuranone analogues.

Graphical abstract: An efficient synthesis of endo,exo-furofuranone derivatives

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Article information

DOI
https://doi.org/10.1039/B206150C
Article type
Communication
Submitted
27 Jun 2002
Accepted
30 Jul 2002
First published
13 Aug 2002

Chem. Commun., 2002, 2042-2043

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An efficient synthesis of endo,exo-furofuranone derivatives

N. A. Swain, R. C. D. Brown and G. Bruton, Chem. Commun., 2002, 2042 DOI: 10.1039/B206150C

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