Issue 8, 2003
From the journal:

Chemical Communications

Cyclopentanes from N-amino-glyconolactams. A synthesis of mannostatin A

Guixian Hu,a   Martin Zimmermann,a   Chepuri Venkata Ramanaa  and  Andrea Vasella*a  

* Corresponding authors

a Laboratorium für Organische Chemie, ETH-Hönggerberg, CH-8093 Zürich, Switzerland
E-mail: vasella@org.chem.ethz.ch.

Abstract

Oxidation of a N-amino-ribonolactam with lead tetraacetate yields two cyclopentanes; the major one was transformed into the α-mannosidase inhibitor mannostatin A.

Graphical abstract: Cyclopentanes from N-amino-glyconolactams. A synthesis of mannostatin A

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Article information

DOI
https://doi.org/10.1039/B301213A
Article type
Communication
Submitted
30 Jan 2003
Accepted
03 Mar 2003
First published
18 Mar 2003

Chem. Commun., 2003, 952-953

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Cyclopentanes from N-amino-glyconolactams. A synthesis of mannostatin A

G. Hu, M. Zimmermann, C. V. Ramana and A. Vasella, Chem. Commun., 2003, 952 DOI: 10.1039/B301213A

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