Issue 12, 2003
From the journal:

Chemical Communications

First crystallographic signature of an acyclic peptidenanorod: molecular mechanism of nanorod formation by a self-assembled tetrapeptide†

Debasish Haldar,a   Arijit Banerjee,a   Michael G. B. Drew,b   Apurba Kumar Dasa  and  Arindam Banerjee*a  

* Corresponding authors

a Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata- 700 032, India
E-mail: bcab@mahendra.iacs.res.in
Tel: +91 33 2473 5904

b Department of Chemistry, The University of Reading, Whiteknights, Reading RG6 6AD, UK

Abstract

A terminally protected acyclic tetrapeptide Boc-Aib-Val-Aib-β-Ala-OMe 1 (Aib: α-aminoisobutyric acid, β-Ala: β-Alanine) self-assembles into a continuous hydrogen-bonded supramolecular helix with an average diameter of 10Å (1nm) starting from a double bend molecular conformation in crystals and further self-assembly of this supramolecular architecture leads to the formation of polydisperse nanorods of diameters 10–40 nm.

Graphical abstract: First crystallographic signature of an acyclic peptide nanorod: molecular mechanism of nanorod formation by a self-assembled tetrapeptide

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B302472P
Article type
Communication
Submitted
04 Mar 2003
Accepted
22 Apr 2003
First published
13 May 2003

Chem. Commun., 2003, 1406-1407

Permissions

Request permissions

First crystallographic signature of an acyclic peptide nanorod: molecular mechanism of nanorod formation by a self-assembled tetrapeptide

D. Haldar, A. Banerjee, M. G. B. Drew, A. K. Das and A. Banerjee, Chem. Commun., 2003, 1406 DOI: 10.1039/B302472P

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements