Six novel halogenated soraphen analogues have been isolated from the wild-type producing organism using precursor directed biosyntheses; the best ‘delivery vehicle’ for the novel starter acids was cinnamate but ortho substituents were not tolerated by the soraphen PKS.
A. M. Hill and B. L. Thompson, Chem. Commun., 2003, 1360 DOI: 10.1039/B303543N
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