Issue 21, 2003
From the journal:

Chemical Communications

Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry

Frédéric Rosu,a   Valérie Gabelica,*a   Kazuo Shin-yab  and  Edwin De Pauwa  

* Corresponding authors

a Department of Chemistry, University of Liege, Sart-Tilman Bat. B6c, B-4000 Liège, Belgium
E-mail: v.gabelica@ulg.ac.be
Fax: (+32)-4-3663413
Tel: (+32)-4-3663432

b Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi Bunkyo-ku, Tokyo 113-0032, Japan

Abstract

Electrospray mass spectrometry (ESI-MS) was used to monitor the kinetics of duplex formation between the human telomeric DNA quadruplex and its complementary strand; the complexation of telomestatin to the G-quadruplex delays the unwinding of the quadruplex structure and formation of the duplex.

Graphical abstract: Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B309394H
Article type
Communication
Submitted
07 Aug 2003
Accepted
04 Sep 2003
First published
30 Sep 2003

Chem. Commun., 2003, 2702-2703

Permissions

Request permissions

Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry

F. Rosu, V. Gabelica, K. Shin-ya and E. De Pauw, Chem. Commun., 2003, 2702 DOI: 10.1039/B309394H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements