A novel, tandem construction of C–N and C–C bonds: facile and one-pot transformation of the Baylis–Hillman adducts into 2-benzazepines†
Abstract
A novel reaction involving tandem construction of C–N and C–C bonds via the simultaneous Ritter and Houben–Hoesch reactions on Baylis–Hillman adducts leading to a convenient, one-pot synthesis of 2-benzazepine derivatives is described. A facile stereoselective transformation of the Baylis–Hillman adducts into (E)- and (Z)-allyl amides is also presented.