An efficient chemical fixation of nitric oxide: convenient and practical synthesis of 1,2,3-oxadiazole 3-oxides†
Abstract
Nitric oxide reacts efficiently with alkynyllithium at low temperature producing 1,2,3-oxadiazole 3-oxides in good yields.
* Corresponding authors
a
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan
E-mail:
taku@ph.bunri-u.ac.jp
Fax: +81-88-655-3051
Tel: +81-88-622-9611
Nitric oxide reacts efficiently with alkynyllithium at low temperature producing 1,2,3-oxadiazole 3-oxides in good yields.
T. Sugihara, K. Kuwahara, A. Wakabayashi, H. Takao, H. Imagawa and M. Nishizawa, Chem. Commun., 2004, 216 DOI: 10.1039/B311382E
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