Issue 13, 2004
From the journal:

Chemical Communications

Interstrand communication between 2′-N-(pyren-1-yl)methyl-2′-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity†

Patrick J. Hrdlicka,‡a   B. Ravindra Babu,‡a   Mads D. Sørensenb  and  Jesper Wengel*a  

* Corresponding authors

a Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, DK-5230 Odense M, Denmark
E-mail: jwe@chem.sdu.dk

b Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark

Abstract

Very efficient interstrand communication systems in nucleic acid duplexes, based on pyrene excimer formation between 2′-N-(pyren-1-yl)methyl-2′-amino-LNA monomers, demonstrate the versatility of functionalized 2′-amino-LNA monomers for Ångström-scale chemical engineering.

Graphical abstract: Interstrand communication between 2′-N-(pyren-1-yl)methyl-2′-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity

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Article information

DOI
https://doi.org/10.1039/B404446K
Article type
Communication
Submitted
29 Mar 2004
Accepted
10 May 2004
First published
04 Jun 2004

Chem. Commun., 2004, 1478-1479

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Interstrand communication between 2′-N-(pyren-1-yl)methyl-2′-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity

P. J. Hrdlicka, B. R. Babu, M. D. Sørensen and J. Wengel, Chem. Commun., 2004, 1478 DOI: 10.1039/B404446K

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