Issue 7, 2004
From the journal:

Organic & Biomolecular Chemistry

Formation of LacNAc mimetics employing novel donor substrates for enzymatic β1→4 galactosylation

Saskia Weingartena  and  Joachim Thiem*a  

* Corresponding authors

a Institute of Organic Chemistry, Hamburg University, Martin-Luther-King-Platz 6, Hamburg, Germany
E-mail: thiem@chemie.uni-hamburg.de
Fax: +49 40 42838 4325
Tel: +49 40 42838 7068

Abstract

In examining C-6 modified 4-nitrophenyl β-D-galactopyranosides as donor structures the β-galactosidase (Bacillus circulans) revealed an unexpectedly broad substrate specificity which allowed successful syntheses of various disaccharide components.

Graphical abstract: Formation of LacNAc mimetics employing novel donor substrates for enzymatic β1→4 galactosylation

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Article information

DOI
https://doi.org/10.1039/B400916A
Article type
Communication
Submitted
20 Jan 2004
Accepted
17 Feb 2004
First published
26 Feb 2004

Org. Biomol. Chem., 2004,2, 961-962

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Formation of LacNAc mimetics employing novel donor substrates for enzymatic β1→4 galactosylation

S. Weingarten and J. Thiem, Org. Biomol. Chem., 2004, 2, 961 DOI: 10.1039/B400916A

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