Issue 2, 2005
From the journal:

Chemical Communications

Novel α-functionally substituted amino acids: diphenylphosphinoglycines†‡

Joachim Heinicke,*a   Normen Peuleckea  and  Peter G. Jonesb  

* Corresponding authors

a Institut für Chemie und Biochemie, Ernst-Moritz-Arndt-Universität Greifswald, Greifswald, Germany
E-mail: heinicke@uni-greifswald.de
Fax: +49 3834 864319
Tel: +49 3834 864318

b Institut für Anorganische und Analytische Chemie der Technischen Universität Braunschweig, Braunschweig, Germany
E-mail: p.jones@tu-bs.de
Fax: +49 0531-391 5387
Tel: +49 0531-391 5382

Abstract

The three-component one-pot reaction of glyoxalic acid hydrate with P–H and N–H compounds allows a convenient access to phosphinoglycines. The molecular structure of 1, determined by X-ray crystallography, some reactions and an alternative formation of phosphinoglycolates are reported.

Graphical abstract: Novel α-functionally substituted amino acids: diphenylphosphinoglycines

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Article information

DOI
https://doi.org/10.1039/B412860E
Article type
Communication
Submitted
20 Aug 2004
Accepted
23 Sep 2004
First published
19 Nov 2004

Chem. Commun., 2005, 262-264

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Novel α-functionally substituted amino acids: diphenylphosphinoglycines

J. Heinicke, N. Peulecke and P. G. Jones, Chem. Commun., 2005, 262 DOI: 10.1039/B412860E

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