Issue 4, 2005

Backbone-extended pyrrolidinepeptide nucleic acids (bepPNA): design, synthesis and DNA/RNA binding studies

Abstract

One-carbon extended conformationally constrained pyrrolidine PNA monomer (bepPNA) has been synthesized, incorporated into PNA sequences at predefined positions, and showed selective RNA binding properties.

Graphical abstract: Backbone-extended pyrrolidine peptide nucleic acids (bepPNA): design, synthesis and DNA/RNA binding studies

Supplementary files

Article information

Article type
Communication
Submitted
03 Sep 2004
Accepted
12 Oct 2004
First published
02 Dec 2004

Chem. Commun., 2005, 495-497

Backbone-extended pyrrolidine peptide nucleic acids (bepPNA): design, synthesis and DNA/RNA binding studies

T. Govindaraju and V. A. Kumar, Chem. Commun., 2005, 495 DOI: 10.1039/B413542C

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