Issue 14, 2005

Synthesis of C2-chiral bifunctionalised spin labels and their application to troponin C

Abstract

An enantiomeric pair of C2-chiral bifunctionalised spin labels having a pyrrolidine nitroxide moiety, whose configurations were determined by X-ray crystal diffraction analysis, was prepared and applied to troponin C whose binding mode of double disulfide linkage was proved by EPR spectroscopy.

Graphical abstract: Synthesis of C2-chiral bifunctionalised spin labels and their application to troponin C

Supplementary files

Article information

Article type
Communication
Submitted
30 Nov 2004
Accepted
28 Jan 2005
First published
11 Feb 2005

Chem. Commun., 2005, 1880-1882

Synthesis of C2-chiral bifunctionalised spin labels and their application to troponin C

S. Chatani, M. Nakamura, H. Akahane, N. Kohyama, M. Taki, T. Arata and Y. Yamamoto, Chem. Commun., 2005, 1880 DOI: 10.1039/B418016J

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