Issue 14, 2005
From the journal:

Chemical Communications

Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

Albrecht Berkessel,*a   Santanu Mukherjee,a   Felix Cleemann,a   Thomas N. Müllera  and  Johann Lexa  

* Corresponding authors

a Institut für Organische Chemie der Universität zu Köln, Greinstrasse 4, Köln, Germany
E-mail: berkessel@uni-koeln.de
Fax: +49-221-470-5102
Tel: +49-221-470-3283

Abstract

Bifunctional organocatalysts of the thiourea-tert-amine type, carrying two “matched” elements of chirality, effect the alcoholytic dynamic kinetic resolution of a variety of azlactones with up to 95% ee.

Graphical abstract: Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

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Article information

DOI
https://doi.org/10.1039/B418666D
Article type
Communication
Submitted
14 Dec 2004
Accepted
26 Jan 2005
First published
15 Feb 2005

Chem. Commun., 2005, 1898-1900

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Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

A. Berkessel, S. Mukherjee, F. Cleemann, T. N. Müller and J. Lex, Chem. Commun., 2005, 1898 DOI: 10.1039/B418666D

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