Issue 35, 2005

Radical-carbanion cyclo-coupling in armed aromatics: overriding steric hindrance to ring closure

Abstract

ω-(2-Halophenyl)alkyl-2-oxazolines were prepared and reacted via base promoted intramolecular coupling of radical with carbanionic centres to yield 1-phenyl-1-oxazolino-indan and -tetralin derivatives containing quaternary C-atoms.

Graphical abstract: Radical-carbanion cyclo-coupling in armed aromatics: overriding steric hindrance to ring closure

Article information

Article type
Communication
Submitted
06 May 2005
Accepted
12 Jul 2005
First published
04 Aug 2005

Chem. Commun., 2005, 4453-4455

Radical-carbanion cyclo-coupling in armed aromatics: overriding steric hindrance to ring closure

M. D. Roydhouse and J. C. Walton, Chem. Commun., 2005, 4453 DOI: 10.1039/B506391D

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