Issue 31, 2005

Novel Pd(ii)-catalysed N,O-bicyclisation as an efficient route to the 6-oxa-2-azabicyclo[3.2.1]octane skeleton

Abstract

1-(Benzyloxycarbonylamino)-hex-5-en-3-ol (5) undergoes a novel Pd(II)/CuCl2-catalysed bicyclisation to furnish the corresponding 6-oxa-2-azabicyclo[3.2.1]octane (6) in good yield.

Graphical abstract: Novel Pd(ii)-catalysed N,O-bicyclisation as an efficient route to the 6-oxa-2-azabicyclo[3.2.1]octane skeleton

Supplementary files

Article information

Article type
Communication
Submitted
12 May 2005
Accepted
08 Jun 2005
First published
04 Jul 2005

Chem. Commun., 2005, 3948-3950

Novel Pd(II)-catalysed N,O-bicyclisation as an efficient route to the 6-oxa-2-azabicyclo[3.2.1]octane skeleton

P. Szolcsányi and T. Gracza, Chem. Commun., 2005, 3948 DOI: 10.1039/B506731F

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