Issue 38, 2005
From the journal:

Chemical Communications

The depth of molecular recognition: voltage-sensitive blockage of synthetic multifunctional pores with refined architecture†

Yoann Baudry,a   Dario Pasini,ab   Masamichi Nishihara,‡a   Naomi Sakaia  and  Stefan Matile*a  

* Corresponding authors

a Department of Organic Chemistry, University of Geneva, Geneva, Switzerland
E-mail: stefan.matile@chiorg.unige.ch
Fax: +41 22 379 5123
Tel: +41 22 379 6523

b On leave from the Department of Organic Chemistry, University of Pavia, Pavia, Italy

Abstract

Voltage-sensitive blockage by ADP, ATP and phytate (IP6) demonstrates that active-site contraction toward the middle of newly synthesized rigid-rod β-barrels provides a general strategy to rationally create and modulate the voltage sensitivity (and to increase the efficiency) of molecular recognition by synthetic multifunctional pores.

Graphical abstract: The depth of molecular recognition: voltage-sensitive blockage of synthetic multifunctional pores with refined architecture

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Article information

DOI
https://doi.org/10.1039/B509610C
Article type
Communication
Submitted
08 Jul 2005
Accepted
09 Aug 2005
First published
05 Sep 2005

Chem. Commun., 2005, 4798-4800

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The depth of molecular recognition: voltage-sensitive blockage of synthetic multifunctional pores with refined architecture

Y. Baudry, D. Pasini, M. Nishihara, N. Sakai and S. Matile, Chem. Commun., 2005, 4798 DOI: 10.1039/B509610C

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