Issue 3, 2005
From the journal:

Organic & Biomolecular Chemistry

Preparation of nitropyridines by nitration of pyridines with nitric acid†

Alan R. Katritzky,*a   Eric F. V. Scriven,a   Suman Majumder,a   Rena G. Akhmedova,a   Anatoliy V. Vakulenko,a   Novruz G. Akhmedov,a   Ramiah Muruganb  and  Khalil A. Abboudc  

* Corresponding authors

a Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL, USA
E-mail: katritzky@chem.ufl.edu
Fax: 3523929199

b Reilly Industries Inc, 1500 South Tibbs Avenue, P.O. Box 42912, Indianapolis, Indiana, USA
E-mail: rmurugan@reillyind.com

c X-ray facility, Department of Chemistry, University of Florida, Gainesville, FL, USA
E-mail: abboud@chem.ufl.edu

Abstract

Nitration of pyridines 1a–o with nitric acid in trifluoroacetic anhydride, gave the corresponding 3-nitropyridines 6a–n in yields of 10–83%.

Graphical abstract: Preparation of nitropyridines by nitration of pyridines with nitric acid

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Article information

DOI
https://doi.org/10.1039/B413285H
Article type
Paper
Submitted
31 Aug 2004
Accepted
22 Oct 2004
First published
10 Jan 2005

Org. Biomol. Chem., 2005,3, 538-541

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Preparation of nitropyridines by nitration of pyridines with nitric acid

A. R. Katritzky, E. F. V. Scriven, S. Majumder, R. G. Akhmedova, A. V. Vakulenko, N. G. Akhmedov, R. Murugan and K. A. Abboud, Org. Biomol. Chem., 2005, 3, 538 DOI: 10.1039/B413285H

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